Powerball Results for Wednesday, October 22, 2025
Winning Numbers
18
37
52
54
60
+
12
PowerPlay2x
White Balls
18, 37, 52, 54, 60
Powerball
12
Power Play
2x
Powerball Draw on Wednesday, October 22, 2025
These are the official Powerball winning numbers for the draw held on Wednesday, October 22, 2025. Powerball draws take place every Monday, Wednesday, and Saturday at 10:59 PM ET. Check your tickets against these numbers to see if you are a winner.